A Systems Approach to Crisis Preparedness and Organizational Resilience

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Antimicrobial Resistance Page 2


Antimicrobial Resistance (AR) is characterized by an organism having the ability to withstand the effects of antibiotic therapy; the result of microbes changing in ways that reduce or eliminate the effectiveness of drugs.

Antimicrobials (antibiotics) have been used since the 1940s; they have greatly reduced illness and deaths from infectious disease.  Their prolonged and, at times, inappropriate widespread use has facilitated the growth of organisms that have adapted to antimicrobial therapy.  The end result is infections that require prolonged treatment, extended hospital stays, and may be more likely to die as a result.

 Problem Pathogens (a few examples)


Methicillin-resistant Staphylococcus aureus                                                                      Vancomycin-resistant Staphylococcus Aureus                                                         Vancomycin-resistant Enterococcus

Clinical Presentation Examples


Basic Problems

Crisis Impact

Action Items


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Date Page Created: Apr 20, 2011 Last Page Update: Feb 5, 2011